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Analyses of an epigenetic switch involved in the activation of pioneer factor FOXA1 leading to the prognostic value of estrogen receptor and FOXA1 co-expression in breast cancer

Forkhead box protein A1 (FOXA1) is a pioneer factor of estrogen receptor α (ER)–chromatin binding and function, yet the role of FOXA1 in breast cancer and the underlying molecular mechanisms have not yet been elucidated. To evaluate gene expression alterations during breast carcinogenesis, FOXA1 exp...

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Detalles Bibliográficos
Autores principales: Jing, Xuan, Liang, Hongping, Hao, Chonghua, Hongxia, Li, Cui, Xiangrong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6782010/
https://www.ncbi.nlm.nih.gov/pubmed/31562808
http://dx.doi.org/10.18632/aging.102250