Sulfated polysaccharide of Sepiella maindroni ink targets Akt and overcomes resistance to the FGFR inhibitor AZD4547 in bladder cancer

Rapid appearance of resistance to fibroblast growth factor receptor (FGFR) inhibitors hampers targeted regimens in bladder cancer. In the present study, we evaluated whether SIP-SII, a sulphated derivative of the polysaccharide in Sepiella maindroni (spineless cuttlefish) ink used in traditional Chi...

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Detalles Bibliográficos
Autores principales: Shan, Liping, Liu, Wei, Zhan, Yunhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2019
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6782013/
https://www.ncbi.nlm.nih.gov/pubmed/31545294
http://dx.doi.org/10.18632/aging.102286

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6782013/
https://www.ncbi.nlm.nih.gov/pubmed/31545294
http://dx.doi.org/10.18632/aging.102286

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