3D spatial organization and network-guided comparison of mutation profiles in Glioblastoma reveals similarities across patients

Glioblastoma multiforme (GBM) is the most aggressive type of brain tumor. Molecular heterogeneity is a hallmark of GBM tumors that is a barrier in developing treatment strategies. In this study, we used the nonsynonymous mutations of GBM tumors deposited in The Cancer Genome Atlas (TCGA) and applied...

Descripción completa

Detalles Bibliográficos
Autores principales: Dincer, Cansu, Kaya, Tugba, Keskin, Ozlem, Gursoy, Attila, Tuncbag, Nurcan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6782092/
https://www.ncbi.nlm.nih.gov/pubmed/31527881
http://dx.doi.org/10.1371/journal.pcbi.1006789

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6782092/
https://www.ncbi.nlm.nih.gov/pubmed/31527881
http://dx.doi.org/10.1371/journal.pcbi.1006789

Ejemplares similares