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Control over single-cell distribution of G1 lengths by WNT governs pluripotency
The link between single-cell variation and population-level fate choices lacks a mechanistic explanation despite extensive observations of gene expression and epigenetic variation among individual cells. Here, we found that single human embryonic stem cells (hESCs) have different and biased differen...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6782112/ https://www.ncbi.nlm.nih.gov/pubmed/31557150 http://dx.doi.org/10.1371/journal.pbio.3000453 |