Cargando…

Control over single-cell distribution of G1 lengths by WNT governs pluripotency

The link between single-cell variation and population-level fate choices lacks a mechanistic explanation despite extensive observations of gene expression and epigenetic variation among individual cells. Here, we found that single human embryonic stem cells (hESCs) have different and biased differen...

Descripción completa

Detalles Bibliográficos
Autores principales: Jang, Jiwon, Han, Dasol, Golkaram, Mahdi, Audouard, Morgane, Liu, Guojing, Bridges, Daniel, Hellander, Stefan, Chialastri, Alex, Dey, Siddharth S., Petzold, Linda R., Kosik, Kenneth S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6782112/
https://www.ncbi.nlm.nih.gov/pubmed/31557150
http://dx.doi.org/10.1371/journal.pbio.3000453