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Control over single-cell distribution of G1 lengths by WNT governs pluripotency
The link between single-cell variation and population-level fate choices lacks a mechanistic explanation despite extensive observations of gene expression and epigenetic variation among individual cells. Here, we found that single human embryonic stem cells (hESCs) have different and biased differen...
| Autores principales: | , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6782112/ https://www.ncbi.nlm.nih.gov/pubmed/31557150 http://dx.doi.org/10.1371/journal.pbio.3000453 |