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Complement and CD4(+) T cells drive context-specific corneal sensory neuropathy

Whether complement dysregulation directly contributes to the pathogenesis of peripheral nervous system diseases, including sensory neuropathies, is unclear. We addressed this important question in a mouse model of ocular HSV-1 infection, where sensory nerve damage is a common clinical problem. Throu...

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Detalles Bibliográficos
Autores principales: Royer, Derek J, Echegaray-Mendez, Jose, Lin, Liwen, Gmyrek, Grzegorz B, Mathew, Rose, Saban, Daniel R, Perez, Victor L, Carr, Daniel JJ
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6783265/
https://www.ncbi.nlm.nih.gov/pubmed/31414985
http://dx.doi.org/10.7554/eLife.48378