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Stereotyped transcriptomic transformation of somatosensory neurons in response to injury
In mice, spared nerve injury replicates symptoms of human neuropathic pain and induces upregulation of many genes in somatosensory neurons. Here we used single cell transcriptomics to probe the effects of partial infraorbital transection of the trigeminal nerve at the cellular level. Uninjured neuro...
Autores principales: | Nguyen, Minh Q, Le Pichon, Claire E, Ryba, Nicholas |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6783272/ https://www.ncbi.nlm.nih.gov/pubmed/31592768 http://dx.doi.org/10.7554/eLife.49679 |
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