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Tristetraprolin targets Nos2 expression in the colonic epithelium

Tristetraprolin (TTP), encoded by the Zfp36 gene, is a zinc-finger protein that regulates RNA stability primarily through association with 3′ untranslated regions (3′ UTRs) of target mRNAs. While TTP is expressed abundantly in the intestines, its function in intestinal epithelial cells (IECs) is unk...

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Detalles Bibliográficos
Autores principales: Eshelman, Melanie A., Matthews, Stephen M., Schleicher, Emily M., Fleeman, Rebecca M., Kawasawa, Yuka Imamura, Stumpo, Deborah J., Blackshear, Perry J., Koltun, Walter A., Ishmael, Faoud T., Yochum, Gregory S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6783411/
https://www.ncbi.nlm.nih.gov/pubmed/31595002
http://dx.doi.org/10.1038/s41598-019-50957-9