HyPer2 imaging reveals temporal and heterogeneous hydrogen peroxide changes in denervated and aged skeletal muscle fibers in vivo

To determine the role of denervation and motor unit turnover in the age-related increase in skeletal muscle oxidative stress, the hydrogen peroxide (H(2)O(2)) specific, genetically-encoded, fluorescent cyto-HyPer2 probe was expressed in mouse anterior tibialis (AT) muscle and compared with ex vivo m...

Descripción completa

Detalles Bibliográficos
Autores principales: Staunton, C. A., Owen, E. D., Pollock, N., Vasilaki, A., Barrett-Jolley, R., McArdle, A., Jackson, M. J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6783413/
https://www.ncbi.nlm.nih.gov/pubmed/31595023
http://dx.doi.org/10.1038/s41598-019-51035-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6783413/
https://www.ncbi.nlm.nih.gov/pubmed/31595023
http://dx.doi.org/10.1038/s41598-019-51035-w

Ejemplares similares