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Functional regulation of von Willebrand factor ameliorates acute ischemia-reperfusion kidney injury in mice

Acute kidney injury (AKI), an abrupt loss of renal function, is often seen in clinical settings and may become fatal. In addition to its hemostatic functions, von Willebrand factor (VWF) is known to play a role in cross-talk between inflammation and thrombosis. We hypothesized that VWF may be involv...

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Detalles Bibliográficos
Autores principales: Ono, Shiro, Matsui, Hideto, Noda, Masashi, Kasuda, Shogo, Yada, Noritaka, Yoshimoto, Kiyomi, Akiyama, Masashi, Miyata, Toshiyuki, Sugimoto, Mitsuhiko, Nishio, Kenji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6783422/
https://www.ncbi.nlm.nih.gov/pubmed/31594992
http://dx.doi.org/10.1038/s41598-019-51013-2