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Fungal dissemination is limited by liver macrophage filtration of the blood

Fungal dissemination into the bloodstream is a critical step leading to invasive fungal infections. Here, using intravital imaging, we show that Kupffer cells (KCs) in the liver have a prominent function in the capture of circulating Cryptococcus neoformans and Candida albicans, thereby reducing fun...

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Detalles Bibliográficos
Autores principales: Sun, Donglei, Sun, Peng, Li, Hongmei, Zhang, Mingshun, Liu, Gongguan, Strickland, Ashley B., Chen, Yanli, Fu, Yong, Xu, Juan, Yosri, Mohammed, Nan, Yuchen, Zhou, Hong, Zhang, Xiquan, Shi, Meiqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6783440/
https://www.ncbi.nlm.nih.gov/pubmed/31594939
http://dx.doi.org/10.1038/s41467-019-12381-5