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Fungal dissemination is limited by liver macrophage filtration of the blood
Fungal dissemination into the bloodstream is a critical step leading to invasive fungal infections. Here, using intravital imaging, we show that Kupffer cells (KCs) in the liver have a prominent function in the capture of circulating Cryptococcus neoformans and Candida albicans, thereby reducing fun...
Autores principales: | Sun, Donglei, Sun, Peng, Li, Hongmei, Zhang, Mingshun, Liu, Gongguan, Strickland, Ashley B., Chen, Yanli, Fu, Yong, Xu, Juan, Yosri, Mohammed, Nan, Yuchen, Zhou, Hong, Zhang, Xiquan, Shi, Meiqing |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6783440/ https://www.ncbi.nlm.nih.gov/pubmed/31594939 http://dx.doi.org/10.1038/s41467-019-12381-5 |
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