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Aβ Seeding as a Tool to Study Cerebral Amyloidosis and Associated Pathology

Misfolded proteins can form aggregates and induce a self-perpetuating process leading to the amplification and spreading of pathological protein assemblies. These misfolded protein assemblies act as seeds of aggregation. In an in vivo exogenous seeding model, both the features of seeds and the posit...

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Detalles Bibliográficos
Autores principales: Friesen, Marina, Meyer-Luehmann, Melanie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6783493/
https://www.ncbi.nlm.nih.gov/pubmed/31632238
http://dx.doi.org/10.3389/fnmol.2019.00233