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Aβ Seeding as a Tool to Study Cerebral Amyloidosis and Associated Pathology
Misfolded proteins can form aggregates and induce a self-perpetuating process leading to the amplification and spreading of pathological protein assemblies. These misfolded protein assemblies act as seeds of aggregation. In an in vivo exogenous seeding model, both the features of seeds and the posit...
Autores principales: | Friesen, Marina, Meyer-Luehmann, Melanie |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6783493/ https://www.ncbi.nlm.nih.gov/pubmed/31632238 http://dx.doi.org/10.3389/fnmol.2019.00233 |
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