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Transient hysteresis and inherent stochasticity in gene regulatory networks

Cell fate determination, the process through which cells commit to differentiated states is commonly mediated by gene regulatory motifs with mutually exclusive expression states. The classical deterministic picture for cell fate determination includes bistability and hysteresis, which enables the pe...

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Detalles Bibliográficos
Autores principales: Pájaro, M., Otero-Muras, I., Vázquez, C., Alonso, A. A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6783536/
https://www.ncbi.nlm.nih.gov/pubmed/31594925
http://dx.doi.org/10.1038/s41467-019-12344-w