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Transient hysteresis and inherent stochasticity in gene regulatory networks
Cell fate determination, the process through which cells commit to differentiated states is commonly mediated by gene regulatory motifs with mutually exclusive expression states. The classical deterministic picture for cell fate determination includes bistability and hysteresis, which enables the pe...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6783536/ https://www.ncbi.nlm.nih.gov/pubmed/31594925 http://dx.doi.org/10.1038/s41467-019-12344-w |