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E. coli primase and DNA polymerase III holoenzyme are able to bind concurrently to a primed template during DNA replication
During DNA replication in E. coli, a switch between DnaG primase and DNA polymerase III holoenzyme (pol III) activities has to occur every time when the synthesis of a new Okazaki fragment starts. As both primase and the χ subunit of pol III interact with the highly conserved C-terminus of single-st...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6783573/ https://www.ncbi.nlm.nih.gov/pubmed/31595021 http://dx.doi.org/10.1038/s41598-019-51031-0 |