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Pharmacokinetics and safety of tadalafil in a paediatric population with pulmonary arterial hypertension: A multiple ascending‐dose study

AIMS: To evaluate the pharmacokinetics and safety of once‐daily (QD) tadalafil in paediatric patients with pulmonary arterial hypertension (PAH) to establish an appropriate dose range for further research. METHODS: This was an open‐label, multicentre, international, multiple‐ascending‐dose study. Pa...

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Detalles Bibliográficos
Autores principales: Small, David, Ferguson‐Sells, Lisa, Dahdah, Nagib, Bonnet, Damien, Landry, John, Li, Baohui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6783595/
https://www.ncbi.nlm.nih.gov/pubmed/31222765
http://dx.doi.org/10.1111/bcp.14039