The Role of a Crystallographically Unresolved Cytoplasmic Loop in Stabilizing the Bacterial Membrane Insertase YidC2

YidC, a bacterial member of the YidC/Alb3/Oxa1 insertase family, mediates membrane protein assembly and insertion. Cytoplasmic loops are known to have functional significance in membrane proteins such as YidC. Employing microsecond-level molecular dynamics (MD) simulations, we show that the crystall...

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Detalles Bibliográficos
Autores principales: Harkey, Thomas, Govind Kumar, Vivek, Hettige, Jeevapani, Tabari, Seyed Hamid, Immadisetty, Kalyan, Moradi, Mahmoud
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6783614/
https://www.ncbi.nlm.nih.gov/pubmed/31595020
http://dx.doi.org/10.1038/s41598-019-51052-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6783614/
https://www.ncbi.nlm.nih.gov/pubmed/31595020
http://dx.doi.org/10.1038/s41598-019-51052-9

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