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CDK4/6 inhibition mitigates stem cell damage in a novel model for taxane‐induced alopecia

Taxanes are a leading cause of severe and often permanent chemotherapy‐induced alopecia. As the underlying pathobiology of taxane chemotherapy‐induced alopecia remains poorly understood, we investigated how paclitaxel and docetaxel damage human scalp hair follicles in a clinically relevant ex vivo o...

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Detalles Bibliográficos
Autores principales: Purba, Talveen S, Ng'andu, Kayumba, Brunken, Lars, Smart, Eleanor, Mitchell, Ellen, Hassan, Nashat, O'Brien, Aaron, Mellor, Charlotte, Jackson, Jennifer, Shahmalak, Asim, Paus, Ralf
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6783643/
https://www.ncbi.nlm.nih.gov/pubmed/31512803
http://dx.doi.org/10.15252/emmm.201911031