Assessing Cardiomyocyte Excitation-Contraction Coupling Site Detection From Live Cell Imaging Using a Structurally-Realistic Computational Model of Calcium Release

Calcium signaling plays a pivotal role in cardiomyocytes, coupling electrical excitation to mechanical contraction of the heart. Determining locations of active calcium release sites, and how their recruitment changes in response to stimuli and in disease states is therefore of central interest in c...

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Detalles Bibliográficos
Autores principales: Ladd, David, Tilūnaitė, Agnė, Roderick, H. Llewelyn, Soeller, Christian, Crampin, Edmund J., Rajagopal, Vijay
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Physiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6783691/
https://www.ncbi.nlm.nih.gov/pubmed/31632297
http://dx.doi.org/10.3389/fphys.2019.01263

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6783691/
https://www.ncbi.nlm.nih.gov/pubmed/31632297
http://dx.doi.org/10.3389/fphys.2019.01263

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