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Hyaluronic acid-curcumin conjugate suppresses the fibrotic functions of myofibroblasts from contractive joint by the PTGER2 demethylation

Joint contracture is a fibrotic complication induced by joint immobilization and trauma, which is characterized as excessive myofibroblast proliferation in joint capsule. The treatments of joint contracture are unsatisfied and patients are suffered from joint dysfunction. Our previous study has show...

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Detalles Bibliográficos
Autores principales: Yu, Dongjie, Zhuang, Ze, Ren, Jianhua, Hu, Xuefeng, Wang, Zhe, Zhang, Jieyu, Luo, Yuansen, Wang, Kun, He, Ronghan, Wang, Yunbing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6783700/
https://www.ncbi.nlm.nih.gov/pubmed/31616564
http://dx.doi.org/10.1093/rb/rbz016