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Hyaluronic acid-curcumin conjugate suppresses the fibrotic functions of myofibroblasts from contractive joint by the PTGER2 demethylation
Joint contracture is a fibrotic complication induced by joint immobilization and trauma, which is characterized as excessive myofibroblast proliferation in joint capsule. The treatments of joint contracture are unsatisfied and patients are suffered from joint dysfunction. Our previous study has show...
Autores principales: | Yu, Dongjie, Zhuang, Ze, Ren, Jianhua, Hu, Xuefeng, Wang, Zhe, Zhang, Jieyu, Luo, Yuansen, Wang, Kun, He, Ronghan, Wang, Yunbing |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6783700/ https://www.ncbi.nlm.nih.gov/pubmed/31616564 http://dx.doi.org/10.1093/rb/rbz016 |
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