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The proper strategy to compress and protect plasmid DNA in the Pluronic L64-electropulse system for enhanced intramuscular gene delivery

Intramuscular expression of functional proteins is a promising strategy for therapeutic purposes. Previously, we developed an intramuscular gene delivery method by combining Pluronic L64 and optimized electropulse, which is among the most efficient methods to date. However, plasmid DNAs (pDNAs) in t...

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Detalles Bibliográficos
Autores principales: He, Yutong, Liu, Yili, Sun, Zhe, Han, Fei, Tang, James Zhenggui, Gao, Rong, Wang, Gang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6783702/
https://www.ncbi.nlm.nih.gov/pubmed/31616566
http://dx.doi.org/10.1093/rb/rby028