A Parallel Phenotypic Versus Target-Based Screening Strategy for RNA-Dependent RNA Polymerase Inhibitors of the Influenza A Virus

Influenza A virus infections cause significant morbidity and mortality, and novel antivirals are urgently needed. Influenza RNA-dependent RNA polymerase (RdRp) activity has been acknowledged as a promising target for novel antivirals. In this study, a phenotypic versus target-based screening strateg...

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Detalles Bibliográficos
Autores principales: Zhao, Xiujuan, Wang, Yanyan, Cui, Qinghua, Li, Ping, Wang, Lin, Chen, Zinuo, Rong, Lijun, Du, Ruikun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6783926/
https://www.ncbi.nlm.nih.gov/pubmed/31491939
http://dx.doi.org/10.3390/v11090826

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6783926/
https://www.ncbi.nlm.nih.gov/pubmed/31491939
http://dx.doi.org/10.3390/v11090826

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