A Spectroscopic Study on Secondary Structure and Thermal Unfolding of the Plant Toxin Gelonin Confirms Some Typical Structural Characteristics and Unravels the Sequence of Thermal Unfolding Events

Gelonin from the Indian plant Gelonium multiflorum belongs to the type I ribosome-inactivating proteins (RIPs). Like other members of RIPs, this toxin glycoprotein inhibits protein synthesis of eukaryotic cells; hence, it is largely used in the construction of immunotoxins composed of cell-targeted...

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Detalles Bibliográficos
Autores principales: Scirè, Andrea, Tanfani, Fabio, Ausili, Alessio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6783991/
https://www.ncbi.nlm.nih.gov/pubmed/31443430
http://dx.doi.org/10.3390/toxins11090483

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6783991/
https://www.ncbi.nlm.nih.gov/pubmed/31443430
http://dx.doi.org/10.3390/toxins11090483

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