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Venomic, Transcriptomic, and Bioactivity Analyses of Pamphobeteus verdolaga Venom Reveal Complex Disulfide-Rich Peptides That Modulate Calcium Channels

Pamphobeteus verdolaga is a recently described Theraphosidae spider from the Andean region of Colombia. Previous reports partially characterized its venom profile. In this study, we conducted a detailed analysis that includes reversed-phase high-performance liquid chromatography (rp-HPLC), calcium i...

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Detalles Bibliográficos
Autores principales: Estrada-Gomez, Sebastian, Cardoso, Fernanda Caldas, Vargas-Muñoz, Leidy Johana, Quintana-Castillo, Juan Carlos, Arenas Gómez, Claudia Marcela, Pineda, Sandy Steffany, Saldarriaga-Cordoba, Monica Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6784019/
https://www.ncbi.nlm.nih.gov/pubmed/31461913
http://dx.doi.org/10.3390/toxins11090496