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Identification of a Novel Saxitoxin Analogue, 12β-Deoxygonyautoxin 3, in the Cyanobacterium, Anabaena circinalis (TA04)

Saxitoxin (STX) and its analogues, the potent voltage-gated sodium channel blockers, are biosynthesized by freshwater cyanobacteria and marine dinoflagellates. We previously identified several biosynthetic intermediates in the extract of the cyanobacterium, Anabaena circinalis (TA04), that are prima...

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Detalles Bibliográficos
Autores principales: Minowa, Takashi, Cho, Yuko, Oshima, Yasukatsu, Konoki, Keiichi, Yotsu-Yamashita, Mari
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6784053/
https://www.ncbi.nlm.nih.gov/pubmed/31527551
http://dx.doi.org/10.3390/toxins11090539