Molecular Determinants of Brevetoxin Binding to Voltage-Gated Sodium Channels

Brevetoxins are produced by dinoflagellates such as Karenia brevis in warm-water red tides and cause neurotoxic shellfish poisoning. They bind to voltage-gated sodium channels at neurotoxin receptor 5, making the channels more active by shifting the voltage-dependence of activation to more negative...

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Detalles Bibliográficos
Autores principales: Konoki, Keiichi, Baden, Daniel G., Scheuer, Todd, Catterall, William A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6784055/
https://www.ncbi.nlm.nih.gov/pubmed/31484365
http://dx.doi.org/10.3390/toxins11090513

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6784055/
https://www.ncbi.nlm.nih.gov/pubmed/31484365
http://dx.doi.org/10.3390/toxins11090513

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