Dynamic Views of the Fc Region of Immunoglobulin G Provided by Experimental and Computational Observations

The Fc portion of immunoglobulin G (IgG) is a horseshoe-shaped homodimer, which interacts with various effector proteins, including Fcγ receptors (FcγRs). These interactions are critically dependent on the pair of N-glycans packed between the two C(H)2 domains. Fucosylation of these N-glycans negati...

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Detalles Bibliográficos
Autores principales: Yanaka, Saeko, Yogo, Rina, Inoue, Rintaro, Sugiyama, Masaaki, Itoh, Satoru G., Okumura, Hisashi, Miyanoiri, Yohei, Yagi, Hirokazu, Satoh, Tadashi, Yamaguchi, Takumi, Kato, Koichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6784063/
https://www.ncbi.nlm.nih.gov/pubmed/31544845
http://dx.doi.org/10.3390/antib8030039

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6784063/
https://www.ncbi.nlm.nih.gov/pubmed/31544845
http://dx.doi.org/10.3390/antib8030039

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