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Dynamic Views of the Fc Region of Immunoglobulin G Provided by Experimental and Computational Observations

The Fc portion of immunoglobulin G (IgG) is a horseshoe-shaped homodimer, which interacts with various effector proteins, including Fcγ receptors (FcγRs). These interactions are critically dependent on the pair of N-glycans packed between the two C(H)2 domains. Fucosylation of these N-glycans negati...

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Detalles Bibliográficos
Autores principales:	Yanaka, Saeko, Yogo, Rina, Inoue, Rintaro, Sugiyama, Masaaki, Itoh, Satoru G., Okumura, Hisashi, Miyanoiri, Yohei, Yagi, Hirokazu, Satoh, Tadashi, Yamaguchi, Takumi, Kato, Koichi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6784063/ https://www.ncbi.nlm.nih.gov/pubmed/31544845 http://dx.doi.org/10.3390/antib8030039

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