Long-Acting HIV-1 Fusion Inhibitory Peptides and their Mechanisms of Action

The clinical application of HIV fusion inhibitor, enfuvirtide (T20), was limited mainly because of its short half-life. Here we designed and synthesized two PEGylated C34 peptides, PEG2kC34 and PEG5kC34, with the PEG chain length of 2 and 5 kDa, respectively, and evaluated their anti-HIV-1 activity...

Descripción completa

Detalles Bibliográficos
Autores principales: Wang, Chen, Cheng, Shuihong, Zhang, Yuanyuan, Ding, Yibo, Chong, Huihui, Xing, Hui, Jiang, Shibo, Li, Xuebing, Ma, Liying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6784077/
https://www.ncbi.nlm.nih.gov/pubmed/31480738
http://dx.doi.org/10.3390/v11090811

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6784077/
https://www.ncbi.nlm.nih.gov/pubmed/31480738
http://dx.doi.org/10.3390/v11090811

Ejemplares similares