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The Application of Ribosome Engineering to Natural Product Discovery and Yield Improvement in Streptomyces
Microbial natural product drug discovery and development has entered a new era, driven by microbial genomics and synthetic biology. Genome sequencing has revealed the vast potential to produce valuable secondary metabolites in bacteria and fungi. However, many of the biosynthetic gene clusters are s...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6784132/ https://www.ncbi.nlm.nih.gov/pubmed/31480298 http://dx.doi.org/10.3390/antibiotics8030133 |