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The Application of Ribosome Engineering to Natural Product Discovery and Yield Improvement in Streptomyces

Microbial natural product drug discovery and development has entered a new era, driven by microbial genomics and synthetic biology. Genome sequencing has revealed the vast potential to produce valuable secondary metabolites in bacteria and fungi. However, many of the biosynthetic gene clusters are s...

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Detalles Bibliográficos
Autores principales: Zhu, Saibin, Duan, Yanwen, Huang, Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6784132/
https://www.ncbi.nlm.nih.gov/pubmed/31480298
http://dx.doi.org/10.3390/antibiotics8030133