Naja atra Cardiotoxin 3 Elicits Autophagy and Apoptosis in U937 Human Leukemia Cells through the Ca(2+)/PP2A/AMPK Axis

Cardiotoxins (CTXs) are suggested to exert their cytotoxicity through cell membrane damage. Other studies show that penetration of CTXs into cells elicits mitochondrial fragmentation or lysosome disruption, leading to cell death. Considering the role of AMPK-activated protein kinase (AMPK) in mitoch...

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Detalles Bibliográficos
Autores principales: Chiou, Jing-Ting, Shi, Yi-Jun, Wang, Liang-Jun, Huang, Chia-Hui, Lee, Yuan-Chin, Chang, Long-Sen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6784133/
https://www.ncbi.nlm.nih.gov/pubmed/31547294
http://dx.doi.org/10.3390/toxins11090527

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6784133/
https://www.ncbi.nlm.nih.gov/pubmed/31547294
http://dx.doi.org/10.3390/toxins11090527

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