Integrated Clarification and Purification of Monoclonal Antibodies by Membrane Based Separation of Aqueous Two-Phase Systems

Therapeutic monoclonal antibodies (mAb) are used for the treatment of numerous serious diseases, which have led to an increasing demand over the last decades. Increased cell density and mAb titer of the cultivation broth lead to great challenges for the subsequent clarification and capture operation...

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Detalles Bibliográficos
Autores principales: Kruse, Thomas, Schmidt, Axel, Kampmann, Markus, Strube, Jochen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6784141/
https://www.ncbi.nlm.nih.gov/pubmed/31544846
http://dx.doi.org/10.3390/antib8030040

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6784141/
https://www.ncbi.nlm.nih.gov/pubmed/31544846
http://dx.doi.org/10.3390/antib8030040

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