Cargando…
Integrated Clarification and Purification of Monoclonal Antibodies by Membrane Based Separation of Aqueous Two-Phase Systems
Therapeutic monoclonal antibodies (mAb) are used for the treatment of numerous serious diseases, which have led to an increasing demand over the last decades. Increased cell density and mAb titer of the cultivation broth lead to great challenges for the subsequent clarification and capture operation...
Autores principales: | Kruse, Thomas, Schmidt, Axel, Kampmann, Markus, Strube, Jochen |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6784141/ https://www.ncbi.nlm.nih.gov/pubmed/31544846 http://dx.doi.org/10.3390/antib8030040 |
Ejemplares similares
-
Integration of Aqueous Two-Phase Extraction as Cell Harvest and Capture Operation in the Manufacturing Process of Monoclonal Antibodies
por: Schmidt, Axel, et al.
Publicado: (2017) -
Purification of Monoclonal Antibodies Using a Fiber Based Cation-Exchange Stationary Phase: Parameter Determination and Modeling
por: Schwellenbach, Jan, et al.
Publicado: (2016) -
Technological and methodical process integration in manufacturing of monoclonal antibodies
por: Gronemeyer, Petra, et al.
Publicado: (2015) -
Membrane-Based Clarification and Fractionation of Red Wine Lees Aqueous Extracts
por: Cassano, Alfredo, et al.
Publicado: (2019) -
Integrated flow-through purification for therapeutic monoclonal antibodies processing
por: Ichihara, Takamitsu, et al.
Publicado: (2018)