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The Use of Myelinating Cultures as a Screen of Glycomolecules for CNS Repair

In vitro cell-based assays have been fundamental in modern drug discovery and have led to the identification of novel therapeutics. We have developed complex mixed central nervous system (CNS) cultures, which recapitulate the normal process of myelination over time and allow the study of several par...

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Detalles Bibliográficos
Autores principales: McCanney, George A., Lindsay, Susan L., McGrath, Michael A., Willison, Hugh J., Moss, Claire, Bavington, Charles, Barnett, Susan C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6784161/
https://www.ncbi.nlm.nih.gov/pubmed/31261710
http://dx.doi.org/10.3390/biology8030052