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Combinatorial Avidity Selection of Mosaic Landscape Phages Targeted at Breast Cancer Cells—An Alternative Mechanism of Directed Molecular Evolution

Low performance of actively targeted nanomedicines required revision of the traditional drug targeting paradigm and stimulated the development of novel phage-programmed, self-navigating drug delivery vehicles. In the proposed smart vehicles, targeting peptides, selected from phage libraries using tr...

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Detalles Bibliográficos
Autores principales: Petrenko, Valery A., Gillespie, James W., Xu, Hai, O’Dell, Tiffany, De Plano, Laura M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6784196/
https://www.ncbi.nlm.nih.gov/pubmed/31454976
http://dx.doi.org/10.3390/v11090785