Back-to-Germline (B2G) Procedure for Antibody Devolution

Bispecific antibodies (bsAbs) with avidity-enhanced specificity can be used to address target cells with increased specificity, ideally binding efficiently to cells that express two cognate antigens, yet not to cells that express only one of those. Building blocks required to generate such bsAbs are...

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Detalles Bibliográficos
Autores principales: Schrade, Anja, Bujotzek, Alexander, Spick, Christian, Wagner, Martina, Goerl, Johannes, Wezler, Xenia, Georges, Guy, Kontermann, Roland E., Brinkmann, Ulrich
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6784197/
https://www.ncbi.nlm.nih.gov/pubmed/31544851
http://dx.doi.org/10.3390/antib8030045

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6784197/
https://www.ncbi.nlm.nih.gov/pubmed/31544851
http://dx.doi.org/10.3390/antib8030045

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