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Back-to-Germline (B2G) Procedure for Antibody Devolution
Bispecific antibodies (bsAbs) with avidity-enhanced specificity can be used to address target cells with increased specificity, ideally binding efficiently to cells that express two cognate antigens, yet not to cells that express only one of those. Building blocks required to generate such bsAbs are...
Autores principales: | Schrade, Anja, Bujotzek, Alexander, Spick, Christian, Wagner, Martina, Goerl, Johannes, Wezler, Xenia, Georges, Guy, Kontermann, Roland E., Brinkmann, Ulrich |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6784197/ https://www.ncbi.nlm.nih.gov/pubmed/31544851 http://dx.doi.org/10.3390/antib8030045 |
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