Regulation of Geldanamycin Biosynthesis by Cluster-Situated Transcription Factors and the Master Regulator PhoP

Geldanamycin and the closely related herbimycins A, B, and C are benzoquinone-type ansamycins with antitumoral activity. They are produced by Streptomyces hygroscopicus var. geldanus, Streptomyces lydicus and Streptomyces autolyticus among other Streptomyces strains. Geldanamycins interact with the...

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Detalles Bibliográficos
Autores principales: Martín, Juan F., Ramos, Angelina, Liras, Paloma
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6784220/
https://www.ncbi.nlm.nih.gov/pubmed/31262015
http://dx.doi.org/10.3390/antibiotics8030087

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6784220/
https://www.ncbi.nlm.nih.gov/pubmed/31262015
http://dx.doi.org/10.3390/antibiotics8030087

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