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To Go or Stay: The Development, Benefit, and Detriment of Tissue-Resident Memory CD8 T Cells during Central Nervous System Viral Infections

CD8 T cells coordinate immune defenses against viral infections of the central nervous system (CNS). Virus-specific CD8 T cells infiltrate the CNS and differentiate into brain-resident memory CD8 T cells (CD8 bT(RM)). CD8 bT(RM) are characterized by a lack of recirculation and expression of phenotyp...

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Detalles Bibliográficos
Autores principales: Mockus, Taryn E., Ren, Heather M., Shwetank, Lukacher, Aron E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6784233/
https://www.ncbi.nlm.nih.gov/pubmed/31514273
http://dx.doi.org/10.3390/v11090842