Microsyntenic Clusters Reveal Conservation of lncRNAs in Chordates Despite Absence of Sequence Conservation

Homologous long non-coding RNAs (lncRNAs) are elusive to identify by sequence similarity due to their fast-evolutionary rate. Here we develop LincOFinder, a pipeline that finds conserved intergenic lncRNAs (lincRNAs) between distant related species by means of microsynteny analyses. Using this tool,...

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Detalles Bibliográficos
Autores principales: Herrera-Úbeda, Carlos, Marín-Barba, Marta, Navas-Pérez, Enrique, Gravemeyer, Jan, Albuixech-Crespo, Beatriz, Wheeler, Grant N., Garcia-Fernàndez, Jordi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6784235/
https://www.ncbi.nlm.nih.gov/pubmed/31450588
http://dx.doi.org/10.3390/biology8030061

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6784235/
https://www.ncbi.nlm.nih.gov/pubmed/31450588
http://dx.doi.org/10.3390/biology8030061

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