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Microsyntenic Clusters Reveal Conservation of lncRNAs in Chordates Despite Absence of Sequence Conservation
Homologous long non-coding RNAs (lncRNAs) are elusive to identify by sequence similarity due to their fast-evolutionary rate. Here we develop LincOFinder, a pipeline that finds conserved intergenic lncRNAs (lincRNAs) between distant related species by means of microsynteny analyses. Using this tool,...
Autores principales: | Herrera-Úbeda, Carlos, Marín-Barba, Marta, Navas-Pérez, Enrique, Gravemeyer, Jan, Albuixech-Crespo, Beatriz, Wheeler, Grant N., Garcia-Fernàndez, Jordi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6784235/ https://www.ncbi.nlm.nih.gov/pubmed/31450588 http://dx.doi.org/10.3390/biology8030061 |
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