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Joint inference and alignment of genome structures enables characterization of compartment-independent reorganization across cell types
BACKGROUND: Comparisons of Hi–C data sets between cell types and conditions have revealed differences in topologically associated domains (TADs) and A/B compartmentalization, which are correlated with differences in gene regulation. However, previous comparisons have focused on known forms of 3D org...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2019
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6784335/ https://www.ncbi.nlm.nih.gov/pubmed/31594535 http://dx.doi.org/10.1186/s13072-019-0308-3 |