Glucosamine impedes transforming growth factor β1-mediated corneal fibroblast differentiation by targeting Krüppel-like factor 4

BACKGROUND: Transforming growth factor (TGF) family members play important roles in the regulation of corneal integrity, and the pathogenesis of corneal fibrosis. Currently, there are no effective agents targeting TGF-β signaling to diminish corneal fibrosis. Glucosamine (GlcN), which is widely used...

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Detalles Bibliográficos
Autores principales: Chen, Ying-Jen, Huang, Shih-Ming, Tai, Ming-Cheng, Chen, Jiann-Torng, Liang, Chang-Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6784344/
https://www.ncbi.nlm.nih.gov/pubmed/31597574
http://dx.doi.org/10.1186/s12929-019-0566-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6784344/
https://www.ncbi.nlm.nih.gov/pubmed/31597574
http://dx.doi.org/10.1186/s12929-019-0566-1

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