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Glucosamine impedes transforming growth factor β1-mediated corneal fibroblast differentiation by targeting Krüppel-like factor 4
BACKGROUND: Transforming growth factor (TGF) family members play important roles in the regulation of corneal integrity, and the pathogenesis of corneal fibrosis. Currently, there are no effective agents targeting TGF-β signaling to diminish corneal fibrosis. Glucosamine (GlcN), which is widely used...
Autores principales: | Chen, Ying-Jen, Huang, Shih-Ming, Tai, Ming-Cheng, Chen, Jiann-Torng, Liang, Chang-Min |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6784344/ https://www.ncbi.nlm.nih.gov/pubmed/31597574 http://dx.doi.org/10.1186/s12929-019-0566-1 |
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