Impaired anandamide/palmitoylethanolamide signaling in hippocampal glutamatergic neurons alters synaptic plasticity, learning, and emotional responses

Endocannabinoid signaling via anandamide (AEA) is implicated in a variety of neuronal functions and considered a promising therapeutic target for numerous emotion-related disorders. The major AEA degrading enzyme is fatty acid amide hydrolase (FAAH). Genetic deletion and pharmacological inhibition o...

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Detalles Bibliográficos
Autores principales: Zimmermann, Tina, Bartsch, Julia C., Beer, Annika, Lomazzo, Ermelinda, Guggenhuber, Stephan, Lange, Maren D., Bindila, Laura, Pape, Hans-Christian, Lutz, Beat
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6784910/
https://www.ncbi.nlm.nih.gov/pubmed/30532004
http://dx.doi.org/10.1038/s41386-018-0274-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6784910/
https://www.ncbi.nlm.nih.gov/pubmed/30532004
http://dx.doi.org/10.1038/s41386-018-0274-7

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