LPA(1/3) overactivation induces neonatal posthemorrhagic hydrocephalus through ependymal loss and ciliary dysfunction

Posthemorrhagic hydrocephalus (PHH) in premature infants is a common neurological disorder treated with invasive neurosurgical interventions. Patients with PHH lack effective therapeutic interventions and suffer chronic comorbidities. Here, we report a murine lysophosphatidic acid (LPA)–induced post...

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Detalles Bibliográficos
Autores principales: Lummis, Nicole C., Sánchez-Pavón, Paloma, Kennedy, Grace, Frantz, Aaron J., Kihara, Yasuyuki, Blaho, Victoria A., Chun, Jerold
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2019
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6785248/
https://www.ncbi.nlm.nih.gov/pubmed/31633020
http://dx.doi.org/10.1126/sciadv.aax2011

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6785248/
https://www.ncbi.nlm.nih.gov/pubmed/31633020
http://dx.doi.org/10.1126/sciadv.aax2011

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