Directed evolution of an α1,3-fucosyltransferase using a single-cell ultrahigh-throughput screening method

Fucosylated glycoconjugates are involved in a variety of physiological and pathological processes. However, economical production of fucosylated drugs and prebiotic supplements has been hampered by the poor catalytic efficiency of fucosyltransferases. Here, we developed a fluorescence-activated cell...

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Detalles Bibliográficos
Autores principales: Tan, Yumeng, Zhang, Yong, Han, Yunbin, Liu, Hao, Chen, Haifeng, Ma, Fuqiang, Withers, Stephen G., Feng, Yan, Yang, Guangyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2019
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6785251/
https://www.ncbi.nlm.nih.gov/pubmed/31633018
http://dx.doi.org/10.1126/sciadv.aaw8451

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6785251/
https://www.ncbi.nlm.nih.gov/pubmed/31633018
http://dx.doi.org/10.1126/sciadv.aaw8451

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